Protein electrophoresis is a test that measures specific proteins in the blood. The test
separates proteins in the blood based on their electrical charge. The protein electrophoresis
test is often used to find abnormal substances called M proteins. The presence of M proteins
can be a sign of a type of cancer called myeloma, or multiple myeloma. Myeloma affects
white blood cells called plasma cells in the bone marrow. Protein electrophoresis also tests
for other proteins and antibodies (immunoglobulins). The protein electrophoresis test is also
used to diagnose other conditions affecting the plasma cells. These include Waldenström
macroglobulinemia, monoclonal gammopathy of undetermined significance (MGUS), and
primary amyloidosis.
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